glucuronidation相关论文
Glucuronidation is the dominating in-vivo metabolism pathway of herbacetin:elucidation of herbacetin
OBJECTIVE To map a comprehensive metabolic pathway of herbacetin in rats,specifically,to elucidate the biotransformation......
尿苷-5’-二磷酸葡萄糖醛酸转移酶(UGT)是药物II相代谢反应最主要的酶,通过催化葡萄糖醛酸与内源性或外源性化学物质发生葡萄糖醛......
目的建立黄芩素葡萄糖醛酸化代谢产物B-7G和B-6G的高效液相色谱方法。方法用Kromasil C18柱(4.6 mm×150 mm,5μm),柱温40℃,流动......
Stereoselective urinary excretion of S-(-)- and R-(+)-propranolol glucuronide following oral adminis
AIM: To study the stereoselectivity of phase Ⅱglucuronidation metabolism of side-chain propranolol in Chinese Hah popul......
The glucuronide metabolites of benproperine were synthesized from mono-hydroxylate metabolites of benproperine that were......
目的建立人UGTlA3催化黄酮类化合物定量构效关系,考察不同结构参数对葡醛酸结合反应的影响。方法采用半经验量子化学计算法MOPAC-AM......
人葡糖醛酸基转移酶(UGT)同工酶在黄酮类化合物Ⅱ相代谢反应中呈重要的作用。本综述总结了近年来国内外学者对黄酮类化合物Ⅱ相代谢......
目的旨在了解银杏黄酮山奈酚代谢的有关酶系及酶动力学参数.方法采用苯巴比妥(PB)、地塞米松(DEX)、β-萘黄酮(BNF)和地非三唑(DIP......